Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition

Residues within processed protein fragments bound to major histocompatibility complex class I (MHC-I) glycoproteins have been considered to function as a series of “independent pegs” that either anchor the peptide (p) to the MHC-I and/or interact with the spectrum of αβ-T-cell receptors (TCRs) speci...

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Autori principali: Theodossis, Alex, Guillonneau, Carole, Welland, Andrew, Ely, Lauren K., Clements, Craig S., Williamson, Nicholas A., Webb, Andrew I., Wilce, Jacqueline A., Mulder, Roger J., Dunstone, Michelle A., Doherty, Peter C., McCluskey, James, Purcell, Anthony W., Turner, Stephen J., Rossjohn, Jamie
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851776/
https://ncbi.nlm.nih.gov/pubmed/20212169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000032107
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