Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition

Residues within processed protein fragments bound to major histocompatibility complex class I (MHC-I) glycoproteins have been considered to function as a series of “independent pegs” that either anchor the peptide (p) to the MHC-I and/or interact with the spectrum of αβ-T-cell receptors (TCRs) speci...

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Bibliografiska uppgifter
Huvudupphovsmän: Theodossis, Alex, Guillonneau, Carole, Welland, Andrew, Ely, Lauren K., Clements, Craig S., Williamson, Nicholas A., Webb, Andrew I., Wilce, Jacqueline A., Mulder, Roger J., Dunstone, Michelle A., Doherty, Peter C., McCluskey, James, Purcell, Anthony W., Turner, Stephen J., Rossjohn, Jamie
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2010
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851776/
https://ncbi.nlm.nih.gov/pubmed/20212169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000032107
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