Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition

Residues within processed protein fragments bound to major histocompatibility complex class I (MHC-I) glycoproteins have been considered to function as a series of “independent pegs” that either anchor the peptide (p) to the MHC-I and/or interact with the spectrum of αβ-T-cell receptors (TCRs) speci...

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Main Authors: Theodossis, Alex, Guillonneau, Carole, Welland, Andrew, Ely, Lauren K., Clements, Craig S., Williamson, Nicholas A., Webb, Andrew I., Wilce, Jacqueline A., Mulder, Roger J., Dunstone, Michelle A., Doherty, Peter C., McCluskey, James, Purcell, Anthony W., Turner, Stephen J., Rossjohn, Jamie
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851776/
https://ncbi.nlm.nih.gov/pubmed/20212169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000032107
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