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Molecular basis of cyclooxygenase enzymes (COXs) selective inhibition
The widely used nonsteroidal anti-inflammatory drugs block the cyclooxygenase enzymes (COXs) and are clinically used for the treatment of inflammation, pain, and cancers. A selective inhibition of the different isoforms, particularly COX-2, is desirable, and consequently a deeper understanding of th...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851773/ https://ncbi.nlm.nih.gov/pubmed/20215464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913377107 |
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