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ATP is required for the release of the anaphase-promoting complex/cyclosome from inhibition by the mitotic checkpoint
The mitotic (or spindle assembly) checkpoint system ensures accurate segregation of chromosomes by delaying anaphase until all chromosomes are correctly attached to the mitotic spindle. This system acts by inhibiting the activity of the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase t...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851749/ https://ncbi.nlm.nih.gov/pubmed/20212161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001875107 |
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