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ATP is required for the release of the anaphase-promoting complex/cyclosome from inhibition by the mitotic checkpoint
The mitotic (or spindle assembly) checkpoint system ensures accurate segregation of chromosomes by delaying anaphase until all chromosomes are correctly attached to the mitotic spindle. This system acts by inhibiting the activity of the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase t...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851749/ https://ncbi.nlm.nih.gov/pubmed/20212161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001875107 |
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