Acute inhibition of superoxide formation and Rac(1) activation by nitric oxide and iloprost in human vascular smooth muscle cells in response to the thromboxane A(2) analogue, U46619

BACKGROUND: The over-production of superoxide ([Formula: see text]) derived from NADPH oxidase (NOX) plays a central role in cardiovascular diseases. By contrast, nitric oxide (NO) and prostacyclin (PGI(2)) are vasculoprotective. The effect of the NO donor, NONOate and iloprost on [Formula: see text...

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Hlavní autoři: Muzaffar, S., Shukla, N., Bond, M., Sala-Newby, G., Angelini, G.D., Newby, A.C., Jeremy, J.Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850987/
https://ncbi.nlm.nih.gov/pubmed/18420399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plefa.2008.01.008
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