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Acute inhibition of superoxide formation and Rac(1) activation by nitric oxide and iloprost in human vascular smooth muscle cells in response to the thromboxane A(2) analogue, U46619
BACKGROUND: The over-production of superoxide ([Formula: see text]) derived from NADPH oxidase (NOX) plays a central role in cardiovascular diseases. By contrast, nitric oxide (NO) and prostacyclin (PGI(2)) are vasculoprotective. The effect of the NO donor, NONOate and iloprost on [Formula: see text...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2850987/ https://ncbi.nlm.nih.gov/pubmed/18420399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plefa.2008.01.008 |
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