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Role of the endothelium and nitric oxide synthases in modulating superoxide formation induced by endotoxin and cytokines in porcine pulmonary arteries

Methods: Intrapulmonary artery (PA) segments were obtained from White Landrace pigs (25–35 kg) and incubated with LPS, IL-1α, and TNF-α and O(2)(• -) release was measured by the superoxide dismutase (SOD) inhibitable reduction of ferricytochrome c. The source of O(2)(• -) formation was determined us...

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Detalhes bibliográficos
Main Authors: Muzaffar, S, Jeremy, J, Angelini, G, Stuart-Smith, K, Shukla, N
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1746752/
https://ncbi.nlm.nih.gov/pubmed/12832676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.58.7.598
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