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Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments

BACKGROUND: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor and a similar structure; pairwise sequence alignments often fail to represent accurately the structural alignments inferr...

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Hlavní autoři: Sierk, Michael L, Smoot, Michael E, Bass, Ellen J, Pearson, William R
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850363/
https://ncbi.nlm.nih.gov/pubmed/20307279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-146
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