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Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments

BACKGROUND: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor and a similar structure; pairwise sequence alignments often fail to represent accurately the structural alignments inferr...

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Detalhes bibliográficos
Main Authors: Sierk, Michael L, Smoot, Michael E, Bass, Ellen J, Pearson, William R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850363/
https://ncbi.nlm.nih.gov/pubmed/20307279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-146
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