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The limits of protein sequence comparison?

Modern sequence alignment algorithms are used routinely to identify homologous proteins, proteins that share a common ancestor. Homologous proteins always share similar structures and often have similar functions. Over the past 20 years, sequence comparison has become both more sensitive, largely be...

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Detalhes bibliográficos
Main Authors: Pearson, William R, Sierk, Michael L
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845305/
https://ncbi.nlm.nih.gov/pubmed/15919194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2005.05.005
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