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Efficient pairwise RNA structure prediction and alignment using sequence alignment constraints

BACKGROUND: We are interested in the problem of predicting secondary structure for small sets of homologous RNAs, by incorporating limited comparative sequence information into an RNA folding model. The Sankoff algorithm for simultaneous RNA folding and alignment is a basis for approaches to this pr...

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Detalhes bibliográficos
Main Authors: Dowell, Robin D, Eddy, Sean R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1579236/
https://ncbi.nlm.nih.gov/pubmed/16952317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-400
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