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Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign

BACKGROUND: Joint alignment and secondary structure prediction of two RNA sequences can significantly improve the accuracy of the structural predictions. Methods addressing this problem, however, are forced to employ constraints that reduce computation by restricting the alignments and/or structures...

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Main Authors: Harmanci, Arif Ozgun, Sharma, Gaurav, Mathews, David H
格式: Artigo
語言:Inglês
出版: BioMed Central 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868766/
https://ncbi.nlm.nih.gov/pubmed/17445273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-130
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