Insulin-like growth factor-binding protein-5 stimulates growth of human intestinal muscle cells by activation of Gαi3

In human intestinal smooth muscle cells, endogenous insulin-like growth factor-I (IGF-I) regulates growth and IGF-binding protein-5 (IGFBP-5) expression. The effects of IGF-I are facilitated by IGFBP-5. We previously showed that IGFBP-5 acts independently of IGF-I in human intestinal muscle to stimu...

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Detalhes bibliográficos
Main Authors: Flynn, Robert S., Mahavadi, Sunila, Murthy, Karnam S., Kellum, John M., Kuemmerle, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Hormones and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850095/
https://ncbi.nlm.nih.gov/pubmed/19808657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00323.2009
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