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The Higher Structure of Chromatin in the LCR of the β-Globin Locus Changes during Development

The β-globin locus control region (LCR) is able to enhance the expression of all globin genes throughout the course of development. However, the chromatin structure of the LCR at the different developmental stages is not well defined. We report DNase I and micrococcal nuclease hypersensitivity, chro...

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Autori principali: Fang, Xiangdong, Yin, Wenxuan, Xiang, Ping, Han, Hemei, Stamatoyannopoulos, George, Li, Qiliang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849742/
https://ncbi.nlm.nih.gov/pubmed/19781549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.09.046
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