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Cooperativeness of the Higher Chromatin Structure of the β-Globin Locus Revealed by the Deletion Mutations of DNase I Hypersensitive site 3 of the LCR

High-level transcription of the globin genes requires the enhancement by a distant element, the locus control region (LCR). Such long-range regulation in vivo involves spatial interaction between transcriptional elements, with intervening chromatin looping out. It has been proposed that the clusteri...

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Bibliografski detalji
Glavni autori: Fang, Xiangdong, Xiang, Ping, Yin, Wenxuan, Stamatoyannopoulos, George, Li, Qiliang
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826273/
https://ncbi.nlm.nih.gov/pubmed/17056066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.09.072
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