Histone acetylation at the human β-globin locus changes with developmental age

To delineate the relationship between epigenetic modifications and hemoglobin switching, we compared the pattern of histone acetylation and pol II binding across the β-globin locus at fetal and adult stages of human development. To make this comparison possible, we introduced an external control int...

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Autores principales: Yin, Wenxuan, Barkess, Gráinne, Fang, Xiangdong, Xiang, Ping, Cao, Hua, Stamatoyannopoulos, George, Li, Qiliang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2007
Materias:
Red Cells
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190615/
https://ncbi.nlm.nih.gov/pubmed/17881636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-091256
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