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Gadolinium Ions Block Mechanosensitive Channels by Altering the Packing and Lateral Pressure of Anionic Lipids

Effects of polyvalent ions on the lateral packing of phospholipids have been known for decades, but the physiological consequences have not been systematically studied. Gd(3+) is a relatively nonspecific agent that blocks mechano-gated channels with a variable affinity. In this study, we show that t...

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Autori principali: Ermakov, Yury A., Kamaraju, Kishore, Sengupta, Krishnendu, Sukharev, Sergei
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849073/
https://ncbi.nlm.nih.gov/pubmed/20303859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.11.044
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