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Mechanosensitive Channel MscS in the Open State: Modeling of the Transition, Explicit Simulations, and Experimental Measurements of Conductance

Mechanosensitive channels of small conductance (MscS) are ubiquitous turgor pressure regulators found in many walled cells and some intracellular organelles. Escherichia coli MscS acting as a tension-activated osmolyte release valve shows a nonsaturable conductance (1.2 nS in a 39 mS/cm electrolyte)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Anishkin, Andriy, Kamaraju, Kishore, Sukharev, Sergei
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442180/
https://ncbi.nlm.nih.gov/pubmed/18591417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810000
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