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Mechanosensitive Channel MscS in the Open State: Modeling of the Transition, Explicit Simulations, and Experimental Measurements of Conductance

Mechanosensitive channels of small conductance (MscS) are ubiquitous turgor pressure regulators found in many walled cells and some intracellular organelles. Escherichia coli MscS acting as a tension-activated osmolyte release valve shows a nonsaturable conductance (1.2 nS in a 39 mS/cm electrolyte)...

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Detalles Bibliográficos
Main Authors: Anishkin, Andriy, Kamaraju, Kishore, Sukharev, Sergei
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442180/
https://ncbi.nlm.nih.gov/pubmed/18591417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810000
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