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Mechanosensitive Channel MscS in the Open State: Modeling of the Transition, Explicit Simulations, and Experimental Measurements of Conductance

Mechanosensitive channels of small conductance (MscS) are ubiquitous turgor pressure regulators found in many walled cells and some intracellular organelles. Escherichia coli MscS acting as a tension-activated osmolyte release valve shows a nonsaturable conductance (1.2 nS in a 39 mS/cm electrolyte)...

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Bibliographic Details
Main Authors: Anishkin, Andriy, Kamaraju, Kishore, Sukharev, Sergei
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442180/
https://ncbi.nlm.nih.gov/pubmed/18591417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810000
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