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The cytoplasmic cage domain of the mechanosensitive channel MscS is a sensor of macromolecular crowding

Cells actively regulate the macromolecular excluded volume of the cytoplasm to maintain the reciprocal fraction of free aqueous solution that is optimal for intracellular processes. However, the mechanisms whereby cells sense this critical parameter remain unclear. The mechanosensitive channel of sm...

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Detalhes bibliográficos
Main Authors: Rowe, Ian, Anishkin, Andriy, Kamaraju, Kishore, Yoshimura, Kenjiro, Sukharev, Sergei
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003192/
https://ncbi.nlm.nih.gov/pubmed/24778428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311114
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