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A Forward Chemical Screen in Zebrafish Identifies a Retinoic Acid Derivative with Receptor Specificity
BACKGROUND: Retinoids regulate key developmental pathways throughout life, and have potential uses for differentiation therapy. It should be possible to identify novel retinoids by coupling new chemical reactions with screens using the zebrafish embryonic model. PRINCIPAL FINDINGS: We synthesized no...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848850/ https://ncbi.nlm.nih.gov/pubmed/20368991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010004 |
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