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A Forward Chemical Screen Using Zebrafish Embryos with Novel 2-Substituted 2H-Chromene Derivatives

We synthesized 2-substituted 2H-chromene derivatives from salicylaldehyde using potassium vinylic borates in the presence of secondary amines. Our goal was to generate novel compounds that might modulate transforming growth factor-β signaling, based on limited rational design. Potassium vinyl triflu...

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Detalhes bibliográficos
Main Authors: Torregroza, Ingrid, Evans, Todd, Das, Bhaskar C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133956/
https://ncbi.nlm.nih.gov/pubmed/19207470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2009.00782.x
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