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Synthesis of function-oriented 2-phenyl-2H-chromene derivatives using L-pipecolinic acid and substituted guanidine organocatalysts

Organocatalytic domino oxa-Michael/aldol reactions between salicylaldehyde with electron deficient olefins are presented. We screened guanidine, 1,1,3,3-tetramethylguanidine (TMG) and L-pipecolinic acid as organocatalysts for this transformation. 3-Substituted 2-phenyl-2H-chromene derivatives are sy...

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Detalhes bibliográficos
Main Authors: Das, Bhaskar C., Mohapatra, Seetaram, Campbell, Philip D., Nayak, Sabita, Mahalingam, Sakkarapalayam M., Evans, Todd
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140427/
https://ncbi.nlm.nih.gov/pubmed/21785516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2010.02.143
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