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A forward chemical screen in zebrafish identifies a retinoic acid derivative with receptor specificity.

Retinoids regulate key developmental pathways throughout life, and have potential uses for differentiation therapy. It should be possible to identify novel retinoids by coupling new chemical reactions with screens using the zebrafish embryonic model.We synthesized novel retinoid analogues and deriva...

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Detaylı Bibliyografya
Asıl Yazarlar: Bhaskar C Das, Kellie McCartin, Ting-Chun Liu, Randall T Peterson, Todd Evans
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2010-04-01
Seri Bilgileri:PLoS ONE
Online Erişim:http://europepmc.org/articles/PMC2848850?pdf=render
Etiketler: Etiketle
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