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eIF5A Promotes Translation Elongation, Polysome Disassembly and Stress Granule Assembly

Stress granules (SGs) are cytoplasmic foci at which untranslated mRNAs accumulate in cells exposed to environmental stress. We have identified ornithine decarboxylase (ODC), an enzyme required for polyamine synthesis, and eIF5A, a polyamine (hypusine)-modified translation factor, as proteins require...

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Hlavní autoři: Li, Chi Ho, Ohn, Takbum, Ivanov, Pavel, Tisdale, Sarah, Anderson, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848580/
https://ncbi.nlm.nih.gov/pubmed/20376341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009942
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