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eIF5A Promotes Translation Elongation, Polysome Disassembly and Stress Granule Assembly
Stress granules (SGs) are cytoplasmic foci at which untranslated mRNAs accumulate in cells exposed to environmental stress. We have identified ornithine decarboxylase (ODC), an enzyme required for polyamine synthesis, and eIF5A, a polyamine (hypusine)-modified translation factor, as proteins require...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848580/ https://ncbi.nlm.nih.gov/pubmed/20376341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009942 |
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