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eIF5A Promotes Translation Elongation, Polysome Disassembly and Stress Granule Assembly

Stress granules (SGs) are cytoplasmic foci at which untranslated mRNAs accumulate in cells exposed to environmental stress. We have identified ornithine decarboxylase (ODC), an enzyme required for polyamine synthesis, and eIF5A, a polyamine (hypusine)-modified translation factor, as proteins require...

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Bibliografiska uppgifter
Huvudupphovsmän: Li, Chi Ho, Ohn, Takbum, Ivanov, Pavel, Tisdale, Sarah, Anderson, Paul
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848580/
https://ncbi.nlm.nih.gov/pubmed/20376341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009942
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