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eIF5A Promotes Translation Elongation, Polysome Disassembly and Stress Granule Assembly

Stress granules (SGs) are cytoplasmic foci at which untranslated mRNAs accumulate in cells exposed to environmental stress. We have identified ornithine decarboxylase (ODC), an enzyme required for polyamine synthesis, and eIF5A, a polyamine (hypusine)-modified translation factor, as proteins require...

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Библиографические подробности
Главные авторы: Li, Chi Ho, Ohn, Takbum, Ivanov, Pavel, Tisdale, Sarah, Anderson, Paul
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848580/
https://ncbi.nlm.nih.gov/pubmed/20376341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009942
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