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A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly

Stress granules (SGs) and processing bodies (PBs) are microscopically visible ribonucleoprotein granules that cooperatively regulate the translation and decay of messenger RNA(1–3). Using an RNA-mediated interference-based screen, we identify 101 human genes required for SG assembly, 39 genes requir...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Ohn, Takbum, Kedersha, Nancy, Hickman, Tyler, Tisdale, Sarah, Anderson, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318256/
https://ncbi.nlm.nih.gov/pubmed/18794846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1783
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