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A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly

Stress granules (SGs) and processing bodies (PBs) are microscopically visible ribonucleoprotein granules that cooperatively regulate the translation and decay of messenger RNA(1–3). Using an RNA-mediated interference-based screen, we identify 101 human genes required for SG assembly, 39 genes requir...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Cell Biol
Main Authors: Ohn, Takbum, Kedersha, Nancy, Hickman, Tyler, Tisdale, Sarah, Anderson, Paul
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318256/
https://ncbi.nlm.nih.gov/pubmed/18794846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1783
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