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A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly

Stress granules (SGs) and processing bodies (PBs) are microscopically visible ribonucleoprotein granules that cooperatively regulate the translation and decay of messenger RNA(1–3). Using an RNA-mediated interference-based screen, we identify 101 human genes required for SG assembly, 39 genes requir...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Cell Biol
Prif Awduron: Ohn, Takbum, Kedersha, Nancy, Hickman, Tyler, Tisdale, Sarah, Anderson, Paul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318256/
https://ncbi.nlm.nih.gov/pubmed/18794846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1783
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