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A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly

Stress granules (SGs) and processing bodies (PBs) are microscopically visible ribonucleoprotein granules that cooperatively regulate the translation and decay of messenger RNA(1–3). Using an RNA-mediated interference-based screen, we identify 101 human genes required for SG assembly, 39 genes requir...

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發表在:Nat Cell Biol
Main Authors: Ohn, Takbum, Kedersha, Nancy, Hickman, Tyler, Tisdale, Sarah, Anderson, Paul
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318256/
https://ncbi.nlm.nih.gov/pubmed/18794846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1783
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