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eIF5A Promotes Translation Elongation, Polysome Disassembly and Stress Granule Assembly

Stress granules (SGs) are cytoplasmic foci at which untranslated mRNAs accumulate in cells exposed to environmental stress. We have identified ornithine decarboxylase (ODC), an enzyme required for polyamine synthesis, and eIF5A, a polyamine (hypusine)-modified translation factor, as proteins require...

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Main Authors: Li, Chi Ho, Ohn, Takbum, Ivanov, Pavel, Tisdale, Sarah, Anderson, Paul
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848580/
https://ncbi.nlm.nih.gov/pubmed/20376341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009942
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