NEDDylation promotes stress granule assembly

Stress granules (SGs) harbour translationally stalled messenger ribonucleoproteins and play important roles in regulating gene expression and cell fate. Here we show that neddylation promotes SG assembly in response to arsenite-induced oxidative stress. Inhibition or depletion of key components of t...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Jayabalan, Aravinth Kumar, Sanchez, Anthony, Park, Ra Young, Yoon, Sang Pil, Kang, Gum-Yong, Baek, Je-Hyun, Anderson, Paul, Kee, Younghoon, Ohn, Takbum
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935812/
https://ncbi.nlm.nih.gov/pubmed/27381497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12125
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