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NEDDylation promotes stress granule assembly

Stress granules (SGs) harbour translationally stalled messenger ribonucleoproteins and play important roles in regulating gene expression and cell fate. Here we show that neddylation promotes SG assembly in response to arsenite-induced oxidative stress. Inhibition or depletion of key components of t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Jayabalan, Aravinth Kumar, Sanchez, Anthony, Park, Ra Young, Yoon, Sang Pil, Kang, Gum-Yong, Baek, Je-Hyun, Anderson, Paul, Kee, Younghoon, Ohn, Takbum
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935812/
https://ncbi.nlm.nih.gov/pubmed/27381497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12125
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