NEDDylation promotes stress granule assembly

Stress granules (SGs) harbour translationally stalled messenger ribonucleoproteins and play important roles in regulating gene expression and cell fate. Here we show that neddylation promotes SG assembly in response to arsenite-induced oxidative stress. Inhibition or depletion of key components of t...

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Опубликовано в: :Nat Commun
Главные авторы: Jayabalan, Aravinth Kumar, Sanchez, Anthony, Park, Ra Young, Yoon, Sang Pil, Kang, Gum-Yong, Baek, Je-Hyun, Anderson, Paul, Kee, Younghoon, Ohn, Takbum
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935812/
https://ncbi.nlm.nih.gov/pubmed/27381497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12125
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