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NEDDylation promotes stress granule assembly

Stress granules (SGs) harbour translationally stalled messenger ribonucleoproteins and play important roles in regulating gene expression and cell fate. Here we show that neddylation promotes SG assembly in response to arsenite-induced oxidative stress. Inhibition or depletion of key components of t...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Jayabalan, Aravinth Kumar, Sanchez, Anthony, Park, Ra Young, Yoon, Sang Pil, Kang, Gum-Yong, Baek, Je-Hyun, Anderson, Paul, Kee, Younghoon, Ohn, Takbum
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935812/
https://ncbi.nlm.nih.gov/pubmed/27381497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12125
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