The Development of Therapeutic Antibodies That Neutralize Homologous and Heterologous Genotypes of Dengue Virus Type 1

Antibody protection against flaviviruses is associated with the development of neutralizing antibodies against the viral envelope (E) protein. Prior studies with West Nile virus (WNV) identified therapeutic mouse and human monoclonal antibodies (MAbs) that recognized epitopes on domain III (DIII) of...

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Bibliografiske detaljer
Main Authors: Shrestha, Bimmi, Brien, James D., Sukupolvi-Petty, Soila, Austin, S. Kyle, Edeling, Melissa A., Kim, Taekyung, O'Brien, Katie M., Nelson, Christopher A., Johnson, Syd, Fremont, Daved H., Diamond, Michael S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848552/
https://ncbi.nlm.nih.gov/pubmed/20369024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000823
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