The Development of Therapeutic Antibodies That Neutralize Homologous and Heterologous Genotypes of Dengue Virus Type 1

Antibody protection against flaviviruses is associated with the development of neutralizing antibodies against the viral envelope (E) protein. Prior studies with West Nile virus (WNV) identified therapeutic mouse and human monoclonal antibodies (MAbs) that recognized epitopes on domain III (DIII) of...

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Main Authors: Shrestha, Bimmi, Brien, James D., Sukupolvi-Petty, Soila, Austin, S. Kyle, Edeling, Melissa A., Kim, Taekyung, O'Brien, Katie M., Nelson, Christopher A., Johnson, Syd, Fremont, Daved H., Diamond, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848552/
https://ncbi.nlm.nih.gov/pubmed/20369024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000823
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