Microgram-order ammonium perfluorooctanoate may activate mouse peroxisome proliferator-activated receptor α, but not human PPARα

Perfluorooctanoic acid (PFOA) is a ligand for peroxisome proliferator-activated receptor (PPAR) α, which exhibits marked species differences in expression and function, especially between rodents and humans. We investigated the functional difference in PFOA response between mice and humans, using a...

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Auteurs principaux: Nakamura, Toshiki, Ito, Yuki, Yanagiba, Yukie, Ramdhan, Doni Hikmat, Kono, Yasuhide, Naito, Hisao, Hayashi, Yumi, Li, Yufei, Aoyama, Toshifumi, Gonzalez, Frank J., Nakajima, Tamie
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848383/
https://ncbi.nlm.nih.gov/pubmed/19751795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2009.09.004
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