Microgram-order ammonium perfluorooctanoate may activate mouse peroxisome proliferator-activated receptor α, but not human PPARα

Perfluorooctanoic acid (PFOA) is a ligand for peroxisome proliferator-activated receptor (PPAR) α, which exhibits marked species differences in expression and function, especially between rodents and humans. We investigated the functional difference in PFOA response between mice and humans, using a...

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Detalhes bibliográficos
Main Authors: Nakamura, Toshiki, Ito, Yuki, Yanagiba, Yukie, Ramdhan, Doni Hikmat, Kono, Yasuhide, Naito, Hisao, Hayashi, Yumi, Li, Yufei, Aoyama, Toshifumi, Gonzalez, Frank J., Nakajima, Tamie
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848383/
https://ncbi.nlm.nih.gov/pubmed/19751795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2009.09.004
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