Proteomics Reveals Novel Oxidative and Glycolytic Mechanisms in Type 1 Diabetic Patients' Skin Which Are Normalized by Kidney-Pancreas Transplantation

BACKGROUND: In type 1 diabetes (T1D) vascular complications such as accelerated atherosclerosis and diffused macro-/microangiopathy are linked to chronic hyperglycemia with a mechanism that is not yet well understood. End-stage renal disease (ESRD) worsens most diabetic complications, particularly,...

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Autors principals: Folli, Franco, Guzzi, Valeria, Perego, Lucia, Coletta, Dawn K., Finzi, Giovanna, Placidi, Claudia, La Rosa, Stefano, Capella, Carlo, Socci, Carlo, Lauro, Davide, Tripathy, Devjit, Jenkinson, Christopher, Paroni, Rita, Orsenigo, Elena, Cighetti, Giuliana, Gregorini, Luisa, Staudacher, Carlo, Secchi, Antonio, Bachi, Angela, Brownlee, Michael, Fiorina, Paolo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848014/
https://ncbi.nlm.nih.gov/pubmed/20360867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009923
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