Inotuzumab Ozogamicin Murine Analog–Mediated B-Cell Depletion Reduces Anti-islet Allo- and Autoimmune Responses

B cells participate in the priming of the allo- and autoimmune responses, and their depletion can thus be advantageous for islet transplantation. Herein, we provide an extensive study of the effect of B-cell depletion in murine models of islet transplantation. Islet transplantation was performed in...

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Detalles Bibliográficos
Autores principales: Carvello, Michele, Petrelli, Alessandra, Vergani, Andrea, Lee, Kang Mi, Tezza, Sara, Chin, Melissa, Orsenigo, Elena, Staudacher, Carlo, Secchi, Antonio, Dunussi-Joannopoulos, Kyri, Sayegh, Mohamed H., Markmann, James F., Fiorina, Paolo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2012
Materias:
Immunology and Transplantation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237644/
https://ncbi.nlm.nih.gov/pubmed/22076927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0684
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