The Glial Glutamate Transporter 1 (GLT1) Is Expressed by Pancreatic β-Cells and Prevents Glutamate-induced β-Cell Death

Glutamate is the major excitatory neurotransmitter of the central nervous system (CNS) and may induce cytotoxicity through persistent activation of glutamate receptors and oxidative stress. Its extracellular concentration is maintained at physiological concentrations by high affinity glutamate trans...

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Główni autorzy: Di Cairano, Eliana S., Davalli, Alberto M., Perego, Lucia, Sala, Silvia, Sacchi, V. Franca, La Rosa, Stefano, Finzi, Giovanna, Placidi, Claudia, Capella, Carlo, Conti, Paola, Centonze, Victoria E., Casiraghi, Francesca, Bertuzzi, Federico, Folli, Franco, Perego, Carla
Format: Artigo
Język:Inglês
Wydane: American Society for Biochemistry and Molecular Biology 2011
Hasła przedmiotowe:
Cell Biology
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077601/
https://ncbi.nlm.nih.gov/pubmed/21335552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.183517
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