The Glial Glutamate Transporter 1 (GLT1) Is Expressed by Pancreatic β-Cells and Prevents Glutamate-induced β-Cell Death

Glutamate is the major excitatory neurotransmitter of the central nervous system (CNS) and may induce cytotoxicity through persistent activation of glutamate receptors and oxidative stress. Its extracellular concentration is maintained at physiological concentrations by high affinity glutamate trans...

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Detalhes bibliográficos
Main Authors: Di Cairano, Eliana S., Davalli, Alberto M., Perego, Lucia, Sala, Silvia, Sacchi, V. Franca, La Rosa, Stefano, Finzi, Giovanna, Placidi, Claudia, Capella, Carlo, Conti, Paola, Centonze, Victoria E., Casiraghi, Francesca, Bertuzzi, Federico, Folli, Franco, Perego, Carla
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077601/
https://ncbi.nlm.nih.gov/pubmed/21335552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.183517
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