The Glial Glutamate Transporter 1 (GLT1) Is Expressed by Pancreatic β-Cells and Prevents Glutamate-induced β-Cell Death

Glutamate is the major excitatory neurotransmitter of the central nervous system (CNS) and may induce cytotoxicity through persistent activation of glutamate receptors and oxidative stress. Its extracellular concentration is maintained at physiological concentrations by high affinity glutamate trans...

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Hlavní autoři: Di Cairano, Eliana S., Davalli, Alberto M., Perego, Lucia, Sala, Silvia, Sacchi, V. Franca, La Rosa, Stefano, Finzi, Giovanna, Placidi, Claudia, Capella, Carlo, Conti, Paola, Centonze, Victoria E., Casiraghi, Francesca, Bertuzzi, Federico, Folli, Franco, Perego, Carla
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077601/
https://ncbi.nlm.nih.gov/pubmed/21335552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.183517
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