Impact of replication timing on non-CpG and CpG substitution rates in mammalian genomes

Neutral nucleotide substitutions occur at varying rates along genomes, and it remains a major issue to unravel the mechanisms that cause these variations and to analyze their evolutionary consequences. Here, we study the role of replication in the neutral substitution pattern. We obtained a high-res...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Chun-Long, Rappailles, Aurélien, Duquenne, Lauranne, Huvet, Maxime, Guilbaud, Guillaume, Farinelli, Laurent, Audit, Benjamin, d'Aubenton-Carafa, Yves, Arneodo, Alain, Hyrien, Olivier, Thermes, Claude
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2010
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847748/
https://ncbi.nlm.nih.gov/pubmed/20103589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.098947.109
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