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Human gene organization driven by the coordination of replication and transcription

In this work, we investigated a large-scale organization of the human genes with respect to putative replication origins. We developed an appropriate multiscale method to analyze the nucleotide compositional skew along the genome and found that in more than one-quarter of the genome, the skew profil...

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Détails bibliographiques
Auteurs principaux: Huvet, Maxime, Nicolay, Samuel, Touchon, Marie, Audit, Benjamin, d'Aubenton-Carafa, Yves, Arneodo, Alain, Thermes, Claude
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950896/
https://ncbi.nlm.nih.gov/pubmed/17675363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6533407
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