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Open chromatin encoded in DNA sequence is the signature of ‘master’ replication origins in human cells

For years, progress in elucidating the mechanisms underlying replication initiation and its coupling to transcriptional activities and to local chromatin structure has been hampered by the small number (approximately 30) of well-established origins in the human genome and more generally in mammalian...

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Detalles Bibliográficos
Main Authors: Audit, Benjamin, Zaghloul, Lamia, Vaillant, Cédric, Chevereau, Guillaume, d'Aubenton-Carafa, Yves, Thermes, Claude, Arneodo, Alain
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764438/
https://ncbi.nlm.nih.gov/pubmed/19671527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp631
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