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Human gene organization driven by the coordination of replication and transcription

In this work, we investigated a large-scale organization of the human genes with respect to putative replication origins. We developed an appropriate multiscale method to analyze the nucleotide compositional skew along the genome and found that in more than one-quarter of the genome, the skew profil...

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Detalles Bibliográficos
Main Authors: Huvet, Maxime, Nicolay, Samuel, Touchon, Marie, Audit, Benjamin, d'Aubenton-Carafa, Yves, Arneodo, Alain, Thermes, Claude
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950896/
https://ncbi.nlm.nih.gov/pubmed/17675363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6533407
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