Safe and targeted anticancer efficacy of a novel class of antioxidant-conjugated difluoro-diarylidenylpiperidones: Differential cytotoxicity in healthy and cancer cells

The development of smart anti-cancer drugs that can selectively kill cancer cells while sparing the surrounding healthy tissues/cells unharmed is of paramount importance for safe and effective cancer therapy. We report a novel class of bifunctional compounds based on diarylidenylpiperidone (DAP) con...

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Hauptverfasser: Selvendiran, Karuppaiyah, Ahmed, Shabnam, Dayton, Alex, Kuppusamy, M. Lakshmi, Tazi, Mia, Bratasz, Anna, Tong, Liyue, Rivera, Brian K., Kálai, Tamás, Hideg, Kálmán, Kuppusamy, Periannan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847669/
https://ncbi.nlm.nih.gov/pubmed/20156552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.02.009
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