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Hypoxia induces chemoresistance in ovarian cancer cells by activation of signal transducer and activator of transcription 3

Signal transducer and activator of transcription 3 (STAT3) is activated in a variety of human cancers, including ovarian cancer. The molecular mechanism by which the STAT3 is activated in cancer cells is poorly understood. We observed that human ovarian xenograft tumors (A2780) in mice were severely...

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Detalhes bibliográficos
Main Authors: Selvendiran, Karuppaiyah, Bratasz, Anna, Kuppusamy, M. Lakshmi, Tazi, Mia F., Rivera, Brian K., Kuppusamy, Periannan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893222/
https://ncbi.nlm.nih.gov/pubmed/19623660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24601
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