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NCX-4016, a nitro-derivative of aspirin, inhibits EGFR and STAT3 signaling and modulates Bcl-2 proteins in cisplatin-resistant human ovarian cancer cells and xenografts

We have previously reported the inhibitory effect of NCX-4016, a nitro derivative of aspirin, on the proliferation of cisplatin-resistant human ovarian cancer cells, in vitro (Bratasz et al., Proc Natl Acad Sci USA 2006; 103:3914–9). In this report we present the results of our study on the mechanis...

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Autores principales: Selvendiran, Karuppaiyah, Bratasz, Anna, Tong, Liyue, Ignarro, Louis J., Kuppusamy, Periannan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890223/
https://ncbi.nlm.nih.gov/pubmed/18196976
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