Active and Repressive Chromatin Are Interspersed without Spreading in an Imprinted Gene Cluster in the Mammalian Genome

The Igf2r imprinted cluster is an epigenetic silencing model in which expression of a ncRNA silences multiple genes in cis. Here, we map a 250 kb region in mouse embryonic fibroblast cells to show that histone modifications associated with expressed and silent genes are mutually exclusive and locali...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Regha, Kakkad, Sloane, Mathew A., Huang, Ru, Pauler, Florian M., Warczok, Katarzyna E., Melikant, Balázs, Radolf, Martin, Martens, Joost H.A., Schotta, Gunnar, Jenuwein, Thomas, Barlow, Denise P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847180/
https://ncbi.nlm.nih.gov/pubmed/17679087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.06.024
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados