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An in vitro ES cell imprinting model shows that imprinted expression of the Igf2r gene arises from an allele-specific expression bias

Genomic imprinting is an epigenetic process that results in parental-specific gene expression. Advances in understanding the mechanism that regulates imprinted gene expression in mammals have largely depended on generating targeted manipulations in embryonic stem (ES) cells that are analysed in vivo...

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Detalhes bibliográficos
Main Authors: Latos, Paulina A., Stricker, Stefan H., Steenpass, Laura, Pauler, Florian M., Huang, Ru, Senergin, Basak H., Regha, Kakkad, Koerner, Martha V., Warczok, Katarzyna E., Unger, Christine, Barlow, Denise P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846269/
https://ncbi.nlm.nih.gov/pubmed/19141673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.032060
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