Silencing and transcriptional properties of the imprinted Airn ncRNA are independent of the endogenous promoter

The Airn macro ncRNA is the master regulator of imprinted expression in the Igf2r imprinted gene cluster where it silences three flanking genes in cis. Airn transcription shows unusual features normally viewed as promoter specific, such as impaired post-transcriptional processing and a macro size. T...

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Autores principales: Stricker, Stefan H, Steenpass, Laura, Pauler, Florian M, Santoro, Federica, Latos, Paulina A, Huang, Ru, Koerner, Martha V, Sloane, Mathew A, Warczok, Katarzyna E, Barlow, Denise P
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2599881/
https://ncbi.nlm.nih.gov/pubmed/19008856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.239
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