A Thermally Stable Form of Bacterial Cocaine Esterase: A Potential Therapeutic Agent for Treatment of Cocaine Abuse

Rhodococcal cocaine esterase (CocE) is an attractive potential treatment for both cocaine overdose and cocaine addiction. CocE directly degrades cocaine into inactive products, whereas traditional small-molecule approaches require blockade of the inhibitory action of cocaine on a diverse array of mo...

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Detalhes bibliográficos
Main Authors: Brim, Remy L., Nance, Mark R., Youngstrom, Daniel W., Narasimhan, Diwahar, Zhan, Chang-Guo, Tesmer, John J. G., Sunahara, Roger K., Woods, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845945/
https://ncbi.nlm.nih.gov/pubmed/20086035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.060806
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